Duration of Therapy - Indiana
by S. Kelly
last updated
Feb 08, 2021 08:35 PM
Indiana State Department of Health
Duration of Therapy
Recommendations for Common Infectious Diseases
| Infection | Treatment Duration1 |
| Cystitis | 3-5 days |
| Pyelonephritis | 7-14 days |
| Catheter-associated UTI | 7-14 days |
| Acute Exacerbations of COPD (when indicated) |
5 days |
| Sinusitis (when indicated) | 5 days |
| Community Acquired Pneumonia (CAP) | 5 days |
| Hospital Acquired Pneumonia (HAP)/ Ventilator Associated Pneumonia (VAP) |
7 days |
| Intra-abdominal infection (cholecystitis, diverticulitis, peritonitis) |
4-5 days |
| Clostridium difficile | 10 days |
| Skin and Soft Tissue | 5-7 days |
| Diabetic Foot Infections | 7-21 days |
| Osteomyelitis |
4-6 weeks |
| Bacteremia2 | Uncomplicated MRSA: 14 days Complicated MRSA: 4-6 weeks Uncomplicated Gram-negative: 7 days Other uncomplicated bacteremia: ~7-14 days |
Notes
- Durations of treatment are highly patient specific and may vary depending on numerous factors. Those listed above are general recommendations from available clinical practice guidelines.
- ID consultation may be helpful to differentiate complicated vs. uncomplicated cases
References
- Mermel LA, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related
infections. Clin Infect Dis. 2009;49:1-45. - Metlay JP, Waterer GW, Long AC, et al. Diagnosis and treatment of adults with community-acquired pneumonia: an official clinical practice guidelines of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med. 2019; 200 (7): e45-67.
- Kalil AC, Metersky ML, Klompas M, et al. Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and American Thoracic Society. Clin Infect Dis. 2016; 63(5): e61-111.
- Stoller JK, et al. Clinical Practice. Acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med.
2002;346:988. - Solomin JS, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children. Clin InfectDis. 2010;50:133-164.
- McDonald LC, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis. 2018; 66(7): e1-48.
- Stevens DL, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59(2);147-59.
- Lipsky BA, et al. 2012 Infectious Diseases Society of America: Diagnosis and treatment of diabetic foot infections. Clin Infect Dis. 2012;54(12):132-173.
- Nicolle LE, Gupta K, Bradley S, et al. Clinical Practice Guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America. Clin Infect Dis. 2019; 68(10): 83-110.
- Gupta K, et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and Pyelonephritisin women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis. 2011;52:e103.
- Hooten TM, et al. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International clinical practice guidelines from the Infectious Diseases Society of America. Clin Infect Dis. 2010;50:62.